{"id":11927,"date":"2016-01-01T17:27:02","date_gmt":"2016-01-01T17:27:02","guid":{"rendered":"http:\/\/lequia-udg.com\/2016\/01\/01\/uv-h2o2degradation-of-the-antidepressants-venlafaxine-and-o-desmethylvenlafaxine-elucidation-of-their-transformation-pathway-and-environmental-fate\/"},"modified":"2024-04-18T17:21:09","modified_gmt":"2024-04-18T17:21:09","slug":"uv-h2o2degradation-of-the-antidepressants-venlafaxine-and-o-desmethylvenlafaxine-elucidation-of-their-transformation-pathway-and-environmental-fate","status":"publish","type":"post","link":"https:\/\/lequia-udg.com\/ca\/2016\/01\/01\/uv-h2o2degradation-of-the-antidepressants-venlafaxine-and-o-desmethylvenlafaxine-elucidation-of-their-transformation-pathway-and-environmental-fate\/","title":{"rendered":"UV\/H2O2degradation of the antidepressants venlafaxine and O-desmethylvenlafaxine: Elucidation of their transformation pathway and environmental fate"},"content":{"rendered":"\t\t
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\r\n\t\t\t\r\n\t\t\t\tAuthors: M\u00aa Jes\u00fas Garc\u00eda-Gal\u00e1n, Alba Anfruns, Rafael Gonzalez-Olmos, Sara Rodr\u00edguez-Mozaz, Joaquim Comas \r\n\t\t\t\r\n\t\t\t<\/h4>\r\n\t\t

\r\n\t\t\t\r\n\t\t\t\tUV\/H2O2degradation of the antidepressants venlafaxine and O-desmethylvenlafaxine: Elucidation of their transformation pathway and environmental fate\r\n\t\t\t\r\n\t\t\t<\/h2>\r\n\t\t<\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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The aim of the present work is to investigate the removal and transformation of the antidepressants venlafaxine (VFX) and its main metabolite O<\/em>-desmethylvenlafaxine (DVFX) upon advanced oxidation with UV\/H2<\/sub>O2<\/sub> under lab conditions. High-resolution mass spectrometry (HRMS) analyses were carried out by means of ultra-high pressure liquid chromatography (UHPLC)-linear ion trap high resolution Orbitrap instrument (LTQ-Orbitrap-MS) in order to elucidate the different transformation products (TPs) generated. The depletion of both VFX and DVFX was very significant, with the 99.9% of both compounds eliminated after 5 and 30 min of reaction, respectively. Eleven TPs for VFX and six for DVFX were detected and their molecular structures elucidated by means of MS2<\/sup> and MS3<\/sup>scans, and the corresponding degradation pathways were proposed. The combined ecotoxicity at different treatment times was evaluated by means of bioluminescence inhibition assays with the marine bacteria Vibrio fischeri<\/em>. Results showed an increase in the ecotoxicity during the UV\/H2<\/sub>O2<\/sub>experiment, especially at those reaction times where the total abundance of TPs was higher.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tInformaci\u00f3 addicional<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t
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Any:<\/strong><\/td>\n2016<\/td>\n<\/tr>\n
Authors:<\/strong><\/td>\nM\u00aa Jes\u00fas Garc\u00eda-Gal\u00e1n, Alba Anfruns, Rafael Gonzalez-Olmos, Sara Rodr\u00edguez-Mozaz, Joaquim Comas<\/td>\n<\/tr>\n
Reference:<\/strong><\/td>\nJournal of Hazardous Materials, Volume 311, 5 July 2016, Pages 70-80<\/td>\n<\/tr>\n
Link:<\/strong><\/td>\nhttp:\/\/dx.doi.org\/10.1016\/j.jhazmat.2016.02.070<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Authors: M\u00aa Jes\u00fas Garc\u00eda-Gal\u00e1n, Alba Anfruns, Rafael Gonzalez-Olmos, Sara Rodr\u00edguez-Mozaz, Joaquim Comas UV\/H2O2degradation of the antidepressants venlafaxine and O-desmethylvenlafaxine: Elucidation of their transformation pathway and environmental fate The aim of the present work is to investigate the removal and transformation of the antidepressants venlafaxine (VFX) and its main metabolite O-desmethylvenlafaxine (DVFX) upon advanced oxidation with … UV\/H2O2degradation of the antidepressants venlafaxine and O-desmethylvenlafaxine: Elucidation of their transformation pathway and environmental fate<\/span>“>Continue reading UV\/H2O2degradation of the antidepressants venlafaxine and O-desmethylvenlafaxine: Elucidation of their transformation pathway and environmental fate<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[64],"tags":[],"class_list":["post-11927","post","type-post","status-publish","format-standard","hentry","category-articles-ca"],"_links":{"self":[{"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/posts\/11927","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/comments?post=11927"}],"version-history":[{"count":1,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/posts\/11927\/revisions"}],"predecessor-version":[{"id":11928,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/posts\/11927\/revisions\/11928"}],"wp:attachment":[{"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/media?parent=11927"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/categories?post=11927"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/tags?post=11927"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}