{"id":11979,"date":"2015-01-01T18:48:34","date_gmt":"2015-01-01T18:48:34","guid":{"rendered":"http:\/\/lequia-udg.com\/2015\/01\/01\/how-can-alcohol-production-be-improved-in-carboxidotrophic-clostridia\/"},"modified":"2024-04-19T15:50:54","modified_gmt":"2024-04-19T15:50:54","slug":"how-can-alcohol-production-be-improved-in-carboxidotrophic-clostridia","status":"publish","type":"post","link":"https:\/\/lequia-udg.com\/ca\/2015\/01\/01\/how-can-alcohol-production-be-improved-in-carboxidotrophic-clostridia\/","title":{"rendered":"How can alcohol production be improved in carboxidotrophic clostridia?"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"11979\" class=\"elementor elementor-11979 elementor-6008\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2cc85fa2 ts-col-stretched-none ts-bg-color-over-image elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2cc85fa2\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-34c2020b ts-bg-color-over-image\" data-id=\"34c2020b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-588943bd ts-align-left elementor-widget elementor-widget-ts_heading\" data-id=\"588943bd\" data-element_type=\"widget\" data-widget_type=\"ts_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t<div class=\"ts-heading-subheading ts-reverse-heading-yes animation-style4\"><h4 class=\"ts-custom-heading ts-custom-subtitle\">\r\n\t\t\t\r\n\t\t\t\tAuthors: Sara Rami\u00f3-Pujol, Ramon Ganigu\u00e9, Llu\u00eds Ba\u00f1eras, Jes\u00fas Colprim                                                                                                         \r\n\t\t\t\r\n\t\t\t<\/h4>\r\n\t\t<h2 class=\"ts-custom-heading ts-custom-heading-title\">\r\n\t\t\t\r\n\t\t\t\tHow can alcohol production be improved in carboxidotrophic clostridia?\r\n\t\t\t\r\n\t\t\t<\/h2>\r\n\t\t<\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-162e693c ts-col-stretched-none ts-bg-color-over-image elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"162e693c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3f141092 ts-bg-color-over-image\" data-id=\"3f141092\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-31c23713 elementor-widget-tablet__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"31c23713\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Clostridia are well-known organisms within the scientific community, and many aspects of their life cycle have been studied. Autotrophic strains are especially interesting as microbial cell factories for industrial purposes. Carboxydotrophic clostridia can use CO<sub>2<\/sub>\/H<sub>2<\/sub> and\/or CO as their only carbon and reducing power sources, and they produce alcohols and acids. Both products can be used as either biofuels or feedstock chemicals for many industrial processes, confirming the control of carboxydotrophic clostridia metabolism as one of the most profitable scientific ambitions to be explored. Here, we review the current state of research on alcohol production by carboxydotrophic clostridia, including a comprehensive overview of their metabolic pathways and the key experimental variables that govern alcohol production. Additionally, the genetic and genomic tools for selective and enhanced solvent production, which are currently under intense development, are discussed. In this context, this review covers the main genetic engineering methods that have been utilized to improve the capabilities of solventogenic carboxydotrophic bacteria.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-26bde07e ts-col-stretched-none ts-bg-color-over-image elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"26bde07e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-62985e93 ts-bg-color-over-image\" data-id=\"62985e93\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5877e15 elementor-widget elementor-widget-accordion\" data-id=\"5877e15\" data-element_type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-9271\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-9271\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Informaci\u00f3 addicional<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-9271\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-9271\"><table style=\"border: hidden;\">\n<tbody>\n<tr style=\"border-bottom: 1px solid #efefef;\">\n<td align=\"right\" width=\"200\"><strong>Year:<\/strong><\/td>\n<td>2015<\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #efefef;\">\n<td align=\"right\" width=\"200\"><strong>Authors:<\/strong><\/td>\n<td>Sara Rami\u00f3-Pujol, Ramon Ganigu\u00e9, Llu\u00eds Ba\u00f1eras, Jes\u00fas Colprim<\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #efefef;\">\n<td align=\"right\" width=\"200\"><strong>Reference:<\/strong><\/td>\n<td>Process Biochemistry, Volume 50, Issue 7, July 2015, Pages 1047-1055<\/td>\n<\/tr>\n<tr style=\"border-bottom: 1px solid #efefef;\">\n<td align=\"right\" width=\"200\"><strong>Link:<\/strong><\/td>\n<td><a href=\"http:\/\/dx.doi.org\/10.1016\/j.procbio.2015.03.019\" target=\"_blank\" rel=\"noopener\">http:\/\/dx.doi.org\/10.1016\/j.procbio.2015.03.019<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-426179e elementor-widget elementor-widget-spacer\" data-id=\"426179e\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Authors: Sara Rami\u00f3-Pujol, Ramon Ganigu\u00e9, Llu\u00eds Ba\u00f1eras, Jes\u00fas Colprim How can alcohol production be improved in carboxidotrophic clostridia? Clostridia are well-known organisms within the scientific community, and many aspects of their life cycle have been studied. Autotrophic strains are especially interesting as microbial cell factories for industrial purposes. Carboxydotrophic clostridia can use CO2\/H2 and\/or CO &hellip; <a href=\"https:\/\/lequia-udg.com\/ca\/2015\/01\/01\/how-can-alcohol-production-be-improved-in-carboxidotrophic-clostridia\/\" class=\"more-link\" title=\"Continue reading <span class=\"screen-reader-text\">How can alcohol production be improved in carboxidotrophic clostridia?<\/span>&#8220;>Continue reading <span class=\"screen-reader-text\">How can alcohol production be improved in carboxidotrophic clostridia?<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[64],"tags":[],"class_list":["post-11979","post","type-post","status-publish","format-standard","hentry","category-articles-ca"],"_links":{"self":[{"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/posts\/11979","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/comments?post=11979"}],"version-history":[{"count":1,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/posts\/11979\/revisions"}],"predecessor-version":[{"id":11980,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/posts\/11979\/revisions\/11980"}],"wp:attachment":[{"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/media?parent=11979"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/categories?post=11979"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lequia-udg.com\/ca\/wp-json\/wp\/v2\/tags?post=11979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}